Biological effect of Ocimum gratissimum (Alfavacão) essential oil in Candida spp
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Keywords

Ocimum gratissimum
Candida spp
Biofilm

How to Cite

CARRASCO, Natália; HOFLING, Jose; PIMENTA, Sarah; MARQUES, Aline; FEIRIA, Simone de; BONI, Giovana. Biological effect of Ocimum gratissimum (Alfavacão) essential oil in Candida spp. Revista dos Trabalhos de Iniciação Científica da UNICAMP, Campinas, SP, n. 27, p. 1–1, 2019. DOI: 10.20396/revpibic2720193066. Disponível em: https://econtents.bc.unicamp.br/eventos/index.php/pibic/article/view/3066. Acesso em: 17 jul. 2024.

Abstract

The use of medicinal plants is a millenarian practice and plays an important role in the development of commercial drugs. Therefore, the present project aimed to determine the antimicrobial activity of Ocimum gratissimum essential oil through the broth microdilution test and evaluate the effect of the essential oil on biofilm formation by Candida albicans. The results showed antifungal activity between 0.25 and 1 mg/mL and decrease of the metabolic activity of C. albicans biofilm between 8-0,5 mg/mL. The essential oil demonstrates antifungal activity against Candida spp. and decreases the metabolic activity of C. albicans when in biofilm formation.

https://doi.org/10.20396/revpibic2720193066
PDF (Português (Brasil))

Todos os trabalhos são de acesso livre, sendo que a detenção dos direitos concedidos aos trabalhos são de propriedade da Revista dos Trabalhos de Iniciação Científica da UNICAMP.

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