Evaluation of the antifungal activity and antibiofilm of the essential oil of Ocimum canum (Alfavaca) in Candida spp

Resumo

Essential oils from plants of the genus Ocimum have demonstrated potential for anti-Candida action, as described in the literature. The objective of the present project was to evaluate the antifungal activity against Candida spp. and the antibiofilm effect of C. albicans of O. canum essential oil. The essential oil showed antifungal activity between 0.0062 to 1 mg / mL and effect on metabolic activity of the biofilm by up to 50% at concentrations of 16-1 mg / mL. The essential oil demonstrates antifungal activity against Candida spp. and decreases the metabolic activity of C. albicans when in biofilm in formation and mature.