Effect of bioactive compounds from beet leaf and stem extract on the prevention or reduction of LDL oxidation and oxidative DNA damage
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Palavras-chave

Bioactive compound
Beet
Reactive oxygen species (ROS).

Como Citar

MASSA, Gabriel Osti; BEZERRA, Rosangela Maria Neves; SILVA, Luiz Guilherme S. da; CASTRO, Ana Paula R. B. de; SIMABUCO, Fernando M. Effect of bioactive compounds from beet leaf and stem extract on the prevention or reduction of LDL oxidation and oxidative DNA damage. Revista dos Trabalhos de Iniciação Científica da UNICAMP, Campinas, SP, n. 26, 2019. DOI: 10.20396/revpibic262018488. Disponível em: https://econtents.bc.unicamp.br/eventos/index.php/pibic/article/view/488. Acesso em: 24 abr. 2024.

Resumo

The objective of this study was to evaluate the antioxidant potential of lyophilized beet leaves through biochemical tests in the prevention or reduction of LDL oxidation and DNA damage. The results of the present study showed that 100 ppm beet leaf extract protects LDL oxidation 100% and maintained HUVECs viability in 48 hours when treated whith 1 ppm beet leaf extract and exposed to oxidized LDL. However as for DNA breakage, this protective effect was not observed.

https://doi.org/10.20396/revpibic262018488
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