Pharmacoresistant seizures associate with widespread cortical thickness atrophy in temporal lobe epilepsy
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Palavras-chave

Temporal lobe epilepsy
Surface-based morphometry
Seizure control

Como Citar

MONTANHER, Lucas; YASUDA, Clarissa; CENDES, Fernando; RIBEIRO, Letícia. Pharmacoresistant seizures associate with widespread cortical thickness atrophy in temporal lobe epilepsy. Revista dos Trabalhos de Iniciação Científica da UNICAMP, Campinas, SP, n. 27, p. 1–1, 2019. DOI: 10.20396/revpibic2720191623. Disponível em: https://econtents.bc.unicamp.br/eventos/index.php/pibic/article/view/1623. Acesso em: 29 mar. 2024.

Resumo

Temporal Lobe Epilepsy (TLE) is the most common epileptic syndrome in adults, and also the most resistant to clinical treatment. Several studies were designed to study brain impacts from focal epilepsies. Surface Based Morphometry (SBM) is a well-validated analytical procedure used to quantify cortical thickness and other parameters in MRI. In the present study, we evaluated cortical involvement in TLE patients in function of seizures control.

https://doi.org/10.20396/revpibic2720191623
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Referências

Long, H.Y., et al. Blood DNA methylation pattern is altered in mesial temporal lobe epilepsy. Sci Rep. 2017, 9;7:43810;

Coyle, A., et al. From resection to ablation: A review of resective surgical options for temporal lobe epilepsy and rationale for an ablation-based approach. Neurol India. 2017, 65(Supplement):S71-S77;

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