Exploring methodologies to obtain the metabolomic profile of biological fluids by LC/MS-MS
No. 26 (2018), Resumos
No. 26 (2018)

Exploring methodologies to obtain the metabolomic profile of biological fluids by LC/MS-MS

Resumos
https://doi.org/10.20396/revpibic262018454
Published 2019-01-07
Flavia Presta Filliettaz
Universidade Estadual de Campinas
Ana Valeria Colnaghi Simionato Cantu
Universidade Estadual de Campinas
Gustavo H. B. Duarte
Universidade Estadual de Campinas
Marcos N. Eberlin
Universidade Estadual de Campinas
Ronei J. Poppi
Universidade Estadual de Campinas
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Keywords

Metabolomic profile
Factorial planning
Biological fluids.

How to Cite

FILLIETTAZ, Flavia Presta; CANTU, Ana Valeria Colnaghi Simionato; DUARTE, Gustavo H. B.; EBERLIN, Marcos N.; POPPI, Ronei J. Exploring methodologies to obtain the metabolomic profile of biological fluids by LC/MS-MS. Revista dos Trabalhos de Iniciação Científica da UNICAMP, Campinas, SP, n. 26, 2019. DOI: 10.20396/revpibic262018454. Disponível em: https://econtents.bc.unicamp.br/eventos/index.php/pibic/article/view/454. Acesso em: 16 aug. 2024.
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Abstract

The investigation of methodologies to obtain the metabolomic profile of blood serum from healthy individuals by LCMS/MS was performed by factorial planning and the number of molecular features as the system answer. Sample preparation, chromatographic and ionization source conditions were optimized, defining the best conditions to obtain the metabolomic profile of biofluids to be applied in future identification of potential tumor biomarkers.

https://doi.org/10.20396/revpibic262018454
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