Palavras-chave
Lymphatic metastases
Sentinel node
Como Citar
Resumo
On the treatment of squamous cell carcinomas of the oral cavity, there is still controversy about the most effective approach for clinically node-negative necks. Currently, the treatment of choice is elective neck dissection followed by histopathological examination for staging. However, the sentinel lymph node biopsy technique proved to be a promising alternative, generating less harm to the patient and being less expensive. Further follow-up is still required to achieve conclusive results and for the method to become a treatment of choice. In this study, we analyzed overall and disease-free survival in patients with squamous cell carcinoma in the oral cavity and with clinically node-negative neck who underwent sentinel lymph node biopsy at our hospital from 1980 to 2013; and we related the survival rates to the presence or absence of tumor relapses. For that, a data survey of the medical records was done, whose results are being submitted to statistical analysis, to be further compared to the medical literature data.
Referências
D’Cruz AK, Vaish R, Kapre N, et al. Elective versus Therapeutic Neck Dissection in Node-Negative Oral Cancer. N Engl J Med. 2015;373(6):521-529.
Coughlin A, Resto VA. Oral cavity squamous cell carcinoma and the clinically n0 neck: The past, present, and future of sentinel lymph node biopsy. Curr Oncol Rep. 2010 Mar;12(2):129-135.
Schiefke F, Akdemir M, Weber A, Akdemir D, Singer S, Frerich B. Function, postoperative morbidity, and quality of life after cervical sentinel node biopsy and after selective neck dissection. Head Neck. 2009 Apr;31(4):503-12.
Chone CT, Magalhães RS, Etchehebere E, Camargo E, Altemani A, Crespo AN. Predictive value of sentinel node biopsy in head and neck cancer. Acta Otolaryngol. 2008 Aug;128(8):920-924.
Melkane AE, Mamelle G, Wycisk G, et al. Sentinel node biopsy in early oral squamous cell carcinomas: A 10-year experience. Laryngoscope. 2012 Aug;122(8):1782-1788.
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