Resumo
Benzimidazoles are antiparasitic agents widely employed in Brazil in livestock farming. Albendazole (ABZ), one of the most effective and used drugs of this class, is highly metabolized (99%) in mammals, being ricobendazole (RBZ) the primarly metabolite. These compounds reach the environment through the excreta of the medicated animals and may impact the environment (soil and water). Therefore, studies about the fate of drugs in the soil-water interface are necessary for the environmental risk assessment. This work aimed to evaluate the sorption kinetic of RBZ onto a clay soil following the OECD 106 Guideline.
Referências
MacKay, A.A. and D. Vasudevan, Polyfunctional Ionogenic Compound Sorption: Challenges and New Approaches To Advance Predictive Models. Environmental Science & Technology, 2012. 46(17): p. 9209-9223.
OECD, Test No. 106: Adsorption -- Desorption Using a Batch Equilibrium Method. 2000: OECD Publishing.
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