Potential adverse drug events from medicines used by patients with chronic kidney disease: pre- and post-transplantation

Resumo

This study aims to identify the medications used by the patient with chronic renal disease in the pre- and post-transplantation and their main potential adverse events. This is a retrospective documentary study, with a quantitative approach. Data from 81 patients submitted to renal transplantation from April to December 2017 were included. Data were analyzed by descriptive statistics. There was high use of polypharmacy. The classes of drugs most used were composed of drugs that act on the alimentary tract and metabolism and on the blood and hematopoietic organs. The five most prescribed drugs were Omeprazole, Folic Acid, Complex B, Prednisone and Bactrim. The potential most frequent, common and serious Adverse Drug Events presented were nausea, dizziness, heart rhythm dysfunction and anaphylaxis. It is observed that there is a high potential for clinically relevant Adverse Drug Events to occur in chronic kidney patients submitted to renal transplantation.